Can lipodystrophy improve over the long term?
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چکیده
Some people may experience one of these fat-related problems while others may have both processes taking place at the same time. Additionally, inside the body, other changes, such as problems managing blood sugar levels and increased cholesterol and other fatty substances in the blood, are taking place. Together, all of these physical and biochemical changes are called the HIV lipodystrophy syndrome.
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PURPOSE During the 24-week PIILR study of protease inhibitor (PI) withdrawal, improved lipids and reduction in intraabdominal visceral fat was seen, however, there was also a loss of subcutaneous limb fat in patients with HIV-lipodystrophy (LD). It was hypothesized that overall improvement in LD may require a longer period of time off PIs. METHOD Follow-up of patients randomized to stop or co...
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